please do answer this question. Thanks

by sarita
(Canada)

Ampicillin 2g was reconstituted with 8 mLs of swi.

1. How much normal saline must you add to get 20 mg/mL concentration?

2. What would the total volume be?

3. With the new concentration mixture, how could you make 4 syringes of 375 mg doses.

Comments for please do answer this question. Thanks

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Answer
by: Chi

Solution.
If 8 mls was used to reconstitute 2g ampicillin, then inside the 8 mls there is 2 g ampicillin.
2 g ampicillin = 2000mg.

To dilute this to 20 mg /ml we need to make up the volume to certain volume. to calculate the volume we need to know the volume that will give us 20 mg/ml.
20 mg is contained in 1 ml
Theefore the 2000mg will be contained in
1 ml/20mg x 2000mg/1
This gives us 100 mls
Water to add is 100 minus the original 8 mls
This gives 92mls Answer.

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